Brian K Law Selected Research

apratoxin S4

1/2021

Inhibition of cotranslational translocation by apratoxin S4: Effects on oncogenic receptor tyrosine kinases and the fate of transmembrane proteins produced in the cytoplasm.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Brian K Law Research Topics

Disease

33	Neoplasms (Cancer) 01/2022 - 12/2002
14	Breast Neoplasms (Breast Cancer) 01/2022 - 11/2008
5	Neoplasm Metastasis (Metastasis) 01/2021 - 11/2006
4	Colorectal Neoplasms (Colorectal Cancer) 07/2022 - 10/2009
4	Carcinogenesis 03/2009 - 12/2002
3	Triple Negative Breast Neoplasms 01/2021 - 04/2017
3	Colonic Neoplasms (Colon Cancer) 01/2016 - 10/2009
3	Chromosomal Instability (Chromosome Stability) 11/2015 - 03/2013
2	Carcinoma (Carcinomatosis) 11/2016 - 12/2002
2	Wounds and Injuries (Trauma) 06/2015 - 03/2014
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022
1	Leukemia 01/2022
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021
1	Multiple Myeloma 01/2019
1	Necrosis 01/2019
1	Reperfusion Injury 01/2018
1	Ischemia 01/2018
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2018
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2016
1	Fibrosis (Cirrhosis) 06/2015
1	Cicatrix (Scar) 06/2015
1	Hemorrhage 06/2015
1	Glioblastoma (Glioblastoma Multiforme) 04/2015

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2006
4	bis(p-chlorophenyl)acetic acid (DDA)IBA 01/2022 - 04/2017
4	DisulfidesIBA 01/2022 - 04/2017
4	Peptide Hydrolases (Proteases)FDA Link 11/2017 - 11/2006
4	Phosphotransferases (Kinase)IBA 04/2017 - 12/2002
4	Sirolimus (Rapamycin)FDA Link 01/2014 - 12/2002
4	DNA (Deoxyribonucleic Acid)IBA 03/2013 - 03/2009
4	Transforming Growth Factor beta (TGF-beta)IBA 10/2008 - 12/2002
3	Pharmaceutical PreparationsIBA 01/2022 - 04/2017
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 12/2011
3	Histones (Histone)IBA 09/2013 - 11/2010
3	Messenger RNA (mRNA)IBA 12/2012 - 11/2006
2	ErbB Receptors (EGF Receptor)IBA 01/2022 - 01/2022
2	Crystallins (Crystallin)IBA 01/2022 - 12/2011
2	Biological ProductsIBA 01/2021 - 01/2019
2	Fluorouracil (Carac)FDA LinkGeneric 01/2019 - 08/2017
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2019 - 10/2005
2	CaspasesIBA 01/2019 - 01/2019
2	Plasminogen Activator Inhibitor 1IBA 11/2017 - 06/2015
2	Small Interfering RNA (siRNA)IBA 11/2017 - 05/2013
2	Cadherins (E-Cadherin)IBA 11/2016 - 11/2008
2	Plasminogen Activators (Plasminogen Activator)IBA 06/2015 - 11/2006
2	Temozolomide (Temodar)FDA LinkGeneric 01/2015 - 10/2009
2	Matrix Metalloproteinases (MMPs)IBA 03/2014 - 11/2006
2	Cyclin D1IBA 05/2013 - 03/2013
2	NF-kappa B (NF-kB)IBA 05/2010 - 03/2009
2	Serine (L-Serine)FDA Link 05/2010 - 03/2009
1	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 07/2022
1	Death Domain ReceptorsIBA 01/2022
1	DNA Methyltransferase 3AIBA 01/2022
1	NucleosidesIBA 01/2022
1	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2022
1	apratoxin S4IBA 01/2021
1	Oncogene Proteins (Oncogene Protein)IBA 01/2021
1	Proline (L-Proline)FDA Link 01/2019
1	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 01/2019
1	Antineoplastic Agents (Antineoplastics)IBA 01/2019
1	Proteasome InhibitorsIBA 01/2019
1	Lapatinib (GW572016)FDA Link 01/2019
1	TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA 01/2019
1	LigandsIBA 01/2019
1	SphingomyelinsIBA 01/2019
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2019
1	ASR352IBA 01/2019
1	Leucovorin (Folinic Acid)FDA Link 01/2019
1	Tyrosine Kinase InhibitorsIBA 01/2019
1	Sirtuin 1IBA 01/2018
1	CathepsinsIBA 11/2017
1	Cysteine (L-Cysteine)FDA Link 11/2017
1	Cystatin CIBA 11/2017
1	Cathepsin DIBA 11/2017
1	grassystatin FIBA 11/2017
1	Protease Inhibitors (Protease Inhibitor)IBA 11/2017
1	Biomarkers (Surrogate Marker)IBA 11/2017
1	matriptaseIBA 09/2017
1	kempopeptin CIBA 09/2017
1	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 09/2017
1	AntibodiesIBA 04/2017
1	Estrogen ReceptorsIBA 04/2017
1	Progesterone Receptors (Progesterone Receptor)IBA 04/2017
1	SmokeIBA 01/2016
1	CarcinogensIBA 01/2016
1	Flap EndonucleasesIBA 01/2016
1	Drug CombinationsIBA 11/2015
1	Adenosine Triphosphate (ATP)IBA 11/2015
1	tiplaxtininIBA 06/2015
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 04/2015
1	vandetanib (ZD6474)IBA 04/2015
1	cediranib (AZD2171)IBA 04/2015
1	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 01/2015
1	NSC666715IBA 01/2015
1	Fibrinolysin FDA Link 03/2014
1	Serine Proteases (Serine Protease)IBA 03/2014
1	Everolimus FDA Link 01/2014
1	MTOR InhibitorsIBA 01/2014

Therapy/Procedure

13	Therapeutics 01/2019 - 10/2005
2	Transplantation 01/2018 - 11/2016